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The conference artwork depicts several possible approaches to preventing Alzheimer's disease and cognitive decline as viewed through a window. These approaches include mental stimulation, exercise, and biomedical research. The conference will examine the current evidence supporting the use of these and other preventive measures for Alzheimer’s disease and cognitive decline. The image was conceived and created by NIH’s Division of Medical Arts and is in the public domain. Please credit 'NIH Medical Arts.'
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NIH State-of-the-Science Conference
Preventing Alzheimer’s Disease
and Cognitive Decline

April 26–28, 2010
Bethesda, Maryland

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State-of-the-Science Panel

Martha L. Daviglus, M.D., Ph.D., M.P.H.
Panel and Conference Chairperson

Professor of Preventive Medicine and Medicine
Department of Preventive Medicine
Feinberg School of Medicine
Northwestern University
Chicago, Illinois

Dr. Daviglus is a professor of preventive medicine in the Department of Preventive Medicine at Northwestern University and is also a professor of medicine at Northwestern's Feinberg School of Medicine. Her research activities have concentrated on the epidemiology and prevention of cardiovascular diseases. She has been involved in investigating associations of traditional cardiovascular and nutritional factors with long-term coronary and cardiovascular morbidity and mortality in middle-aged and older men and women. She has developed expertise in linking and analyzing Health Care Financing Administration (Medicare) data as endpoints in longitudinal studies. Dr. Daviglus' other research interests focus on the benefits in older age, in terms of health care costs and health-related quality of life, associated with favorable cardiovascular risk profile.

Carl C. Bell, M.D.
Dr. Bell is the Director the Institute for Juvenile Research in the Department of Psychiatry at the University of Illinois at Chicago. He is also President and Chief Executive Officer of the Community Mental Health Council, Inc, a comprehensive community mental health center located on Chicago’s Southside. His clinical interests include mental wellness, violence prevention, traumatic stress caused by violence, and HIV/AIDS youth prevention.

Wade Berrettini, M.D., Ph.D.
Dr. Berrettini is the Karl E. Rickels Professor of Psychiatry in the Department of Psychiatry and Director of the Center for Neurobiology and Behavior at the University of Pennsylvania. His research interests have focused on genetic and biologic influences on brain disorders and behavior, specifically, the genetics and pharmacogenetics of mood disorders, addictions, epilepsy and eating disorders.

Phyllis E. Bowen, Ph.D.
Dr. Bowen is a Professor Emerita of Human Nutrition in the Department of Kinesiology and Nutrition at the University of Illinois at Chicago. Her research interests have focused on the role of antioxidants in diseases where oxidative stress is an important driving force. Recent studies have focused on the role of lycopene in the prevention and treatment of prostate cancer and whether the glucose and triglycerides after eating has a role in transient oxidative stress and inflammation, especially in the context of diabetes and metabolic syndrome.

Elaine Sanders-Bush, Ph.D.
Dr. Sanders-Bush is a Professor of Pharmacology and Psychiatry at Vanderbilt University Medical Center. Her research interests include the structure, function, and regulation of two receptors for serotonin, an important neurotransmitter that plays a role in cognition, appetite and mood and in the action of antipsychotic and hallucinogenic drugs.

Edward Sander Connolly, Jr., M.D.
Dr. Connolly is a Professor in the Department of Neurological Surgery at Columbia University. His clinical research efforts have been directed at improving the functional outcome of patients with cerebrovascular emergencies (strokes), as well as the cognitive outcome of patients undergoing cerebral revascularization. His basic research interests span the spectrum of cerebrovascular disease, as well as the genetics of familial cerebral aneurysms.

Nancy Jean Cox, Ph.D.

Dr. Cox is a Professor and Chief of Genetic Medicine at the University of Chicago. Her research interests have focused on developing methods for analyzing complex traits from a genetic standpoint. Although most of the methodology development has been driven by research conducted on type 2 diabetes, her research interests extend to other complex disorders, including type 1 diabetes, diabetic complications, asthma, breast cancer, mesothelioma, stuttering, and psychiatric disorders.

Jacqueline M. Dunbar-Jacob, Ph.D., R.N., FAAN

Dr. Dunbar-Jacob is Dean and Professor of the School of Nursing and Professor of Psychology, Epidemiology, and Occupational Therapy at the University of Pittsburgh. Her research has been focused on patient compliance, including medication adherence. She has worked with a variety of patient populations including those affected by rheumatologic conditions, cardiovascular risk factors, diabetes, AIDS, cancer screening, and transplantation.

Evelyn C. Granieri, M.D., M.P.H., M.S.Ed.
Dr. Granieri is Chief of the Division of Geriatric Medicine and Aging in the College of Physicians and Surgeons at Columbia University and is also on staff at New York Presbyterian Hospital. A nationally-recognized geriatric educator, she is board-certified in geriatric medicine and internal medicine.

Gail Gibson Hunt

Ms. Hunt is President and Chief Executive Officer for the National Alliance for Caregiving. Based in Bethesda, Maryland, this nonprofit coalition of over 40 national groups conducts national research, outreach, and public awareness programs to support family caregivers of older and disabled persons.

Kathleen McGarry, Ph.D.
Dr. McGarry is a Professor in the Department of Economics at the University of California, Los Angeles. Her research focuses on the economics of aging with particular attention paid to the transfer of resources within families and the role of public transfer and insurance programs. Much of her current work is in the area of health economics where she has been examining the relationship between insurance coverage and the financial well-being of elderly individuals.

Dinesh Patel, M.D.
Dr. Patel is a Senior Geriatrician at the Charles E. Smith Life Communities and Assistant Clinical Professor of Medicine at George Washington University School of Medicine. He has been identified as a specialist in Internal Medicine/Geriatric Medicine by the Board of Physician Quality Assurance of Maryland. His clinical interests focus on geriatric cardiology and dementia.

Arnold L. Potosky, Ph.D.
Dr. Potosky is Professor of Oncology and Director of Health Services Research in the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center. His research is directed towards dissemination of cancer-related detection and treatment services, and the connection between care delivery and patient health outcomes in diverse populations treated in general clinical practice.

Donald Silberberg, M.D.

Dr. Silberberg is a Professor in the Department of Neurology at the University of Pennsylvania Medical Center. A board-certified neurologist, his research and clinical activities have focused on multiple sclerosis and related disorders, and on metabolic causes of neonatal injury. A parallel, increasing focus has been on clinical neuroscience in the developing world.

Maurizio Trevisan, M.D., M.S.
Dr. Trevisan is the Executive Vice Chancellor and Chief Executive Officer of the Health Sciences System in the Nevada System of Higher Education. He is also Professor of Medicine in the University of Nevada School of Medicine. His research interests focus on the role of life style and metabolic factors in the etiology and prevention of cardiovascular disease with a focus on the role of diet and alcohol use.

 




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