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DCIS conference artwork


NIH State-of-the-Science Conference:
Diagnosis and Management of
Ductal Carcinoma in Situ (DCIS)

September 22-24, 2009
Bethesda, Maryland

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Sponsors

 

National Cancer Institute logo    Consensus Development Program logo
National Cancer Institute
Office of Medical Applications of Research
of the National Institutes of Health

Co-sponsors

Office of Research on Women's Health
Office of Research on Women's Health

Partners

Agency for Healthcare Research and Quality logo     Centers for Disease Control and Prevention logo    U.S. Food and Drug Administration
Agency for Healthcare Research and Quality
Centers for Disease Control and Prevention
U.S. Food and Drug Administration

Agenda

 

Tuesday, September 22, 2009

8:30 a.m.

Opening Remarks
Peter Greenwald, M.D., Dr.P.H.
Director
Division of Cancer Prevention
National Cancer Institute
National Institutes of Health

 

Worta McCaskill-Stevens, M.D., M.S.
Program Director
Breast Prevention and Minority-Based Community Oncology Program
Community Oncology and Prevention Trials Research Group
Division of Cancer Prevention
National Cancer Institute
National Institutes of Health

8:40 a.m.  Charge to the Panel
Jennifer Miller Croswell, M.D.
Acting Director
Office of Medical Applications of Research
Office of the Director
National Institutes of Health
8:50 a.m.  Conference Overview and Panel Activities
Carmen J. Allegra, M.D.
Panel and Conference Chairperson
Chief, Hematology and Oncology
Associate Director for Clinical and Translational Research
Shands Cancer Center
University of Florida
9:00 a.m.  Terminology, Natural History, and Taxonomy of DCIS
D. Craig Allred, M.D.
Director, Breast Pathology
Professor, Pathology and Immunology
Washington University School of Medicine
I. What are the incidence and prevalence of DCIS and its specific pathologic subtypes, and how are incidence and prevalence influenced by mode of detection, population characteristics, and other risk factors?
9:20 a.m. 

Epidemiology of DCIS
Karla Kerlikowske, M.D., M.S.
Professor of Medicine, Epidemiology and Biostatistics
University of California at San Francisco School of Medicine

9:40 a.m. 

Mode of Detection & Secular Time
Etta D. Pisano, M.D.
Kenan Professor of Radiology and Biomedical Engineering
Vice Dean for Academic Affairs
Director, Biomedical Research Imaging Center
Director, TraCS Institute
University of North Carolina School of Medicine

10:00 a.m.  Evidence-Based Practice Center Presentation I: The Incidence and Prevalence of DCIS and the Influence of Mode of Detection, Population Characteristics, and Other Risk Factors
Beth A. Virnig, Ph.D., M.P.H. 
Professor
Division of Health Policy and Management
University of Minnesota School of Public Health
10:20 a.m.  Discussion
11:00 a.m.  Sentinel Lymph Node Biopsy and Management of the Axilla
Thomas B. Julian, M.D., F.A.C.S.
Associate Director, Breast Care Center
West Penn Allegheny Health System
Associate Professor, Human Oncology
Drexel University College of Medicine
Senior Director, Medical Affairs
National Surgical Adjuvant Breast and Bowel Project (NSABP)
11:20 a.m.  MRI in Patients Diagnosed With DCIS
Constance D. Lehman, M.D., Ph.D.
Vice Chair and Professor of Radiology
Section Head, Breast Imaging
University of Washington School of Medicine
Director of Medical Imaging
Seattle Cancer Care Alliance
11:40 a.m.  Evidence-Based Practice Center Presentation II: The Impact of Magnetic Resonance Imaging
and Sentinel Lymph Node Biopsy on Important Outcomes in Patients Diagnosed with DCIS
Todd M. Tuttle, M.D.
Professor
Department of Surgery
University of Minnesota Medical School
12:00 p.m. 

Discussion

12:30 p.m.  Lunch
Panel Executive Session
II. How does the use of MRI or sentinel lymph node biopsy impact important outcomes in patients diagnosed with DCIS?
 

11:00 a.m. 
Sentinel Lymph Node Biopsy and Management of the Axilla
Thomas B. Julian, M.D., F.A.C.S.
Associate Director, Breast Care Center
West Penn Allegheny Health System
Associate Professor, Human Oncology
Drexel University College of Medicine
Senior Director, Medical Affairs
National Surgical Adjuvant Breast and Bowel Project (NSABP)

11:20 a.m.  MRI in Patients Diagnosed With DCIS
Constance D. Lehman, M.D., Ph.D.
Vice Chair and Professor of Radiology
Section Head, Breast Imaging
University of Washington School of Medicine
Director of Medical Imaging
Seattle Cancer Care Alliance
11:40 a.m.  Evidence-Based Practice Center Presentation II: The Impact of Magnetic Resonance Imaging
and Sentinel Lymph Node Biopsy on Important Outcomes in Patients Diagnosed with DCIS
Todd M. Tuttle, M.D.
Professor
Department of Surgery
University of Minnesota Medical School
12:00 p.m.  Discussion
12:30 p.m.  Lunch
Panel Executive Session
III. How do local control and systemic outcomes vary in DCIS based on tumor and patient characteristics?
1:30 p.m. 

Local Control of DCIS Based on Tumor and Patient Characteristics:
The Surgeon’s Perspective
Lisa A. Newman, M.D., M.P.H., F.A.C.S.
Director, Breast Care Center
Professor of Surgery
University of Michigan Comprehensive Cancer Center

1:50 p.m.  Local and Systemic Outcomes in DCIS Based on Tumor and Patient Characteristics: The
Pathologist’s Perspective
Stuart Schnitt, M.D.
Director, Division of Anatomic Pathology
Beth Israel Deaconess Medical Center
Professor of Pathology
Harvard Medical School
2:10 p.m.  Meta-Analysis of DCIS Trials: Outcomes From the Early Breast Cancer Trialists’ Collaborative Group
Sarah C. Darby, Ph.D.
Professor of Medical Statistics
Clinical Trials Service Unit
University of Oxford
2:30 p.m.  Local and Systemic Outcomes in DCIS Based on Tumor and Patient Characteristics: The Radiation Oncologist’s Perspective
Nina Bijker, M.D., Ph.D. 
Department of Radiation Oncology
Academic Medical Center
University of Amsterdam
2:50 p.m.  DCIS Outcomes in Breast Cancer Chemoprevention Trials
Victor G. Vogel III, M.D., M.H.S.
National Vice President, Research
American Cancer Society
3:10 p.m.  Evidence-Based Practice Center Presentation III: Tumor and Patient Characteristics and
Associated Outcomes in DCIS
Tatyana A. Shamliyan, M.D., M.S.
Research Associate
Division of Health Policy and Management
University of Minnesota School of Public Health
3:30 p.m. 

Discussion

4:30 p.m.  The Impact of Radiation Therapy on DCIS Outcomes
Lawrence J. Solin, M.D., F.A.C.R.
Chairman
Department of Radiation Oncology
Albert Einstein Medical Center
4:50 p.m.  The Impact of Surgery on DCIS Outcomes: The Van Nuys Prognostic Index
Melvin J. Silverstein, M.D.
Professor of Surgery
University of Southern California Heck School of Medicine
Director, Hoag Breast Program
Hoag Memorial Hospital Presbyterian
5:10 p.m.  Discussion
5:30 p.m. Adjournment


Wednesday, September 23, 2009

IV. In patients with DCIS, what is the impact of surgery, radiation, and systemic treatment on outcomes?
8:30 a.m. 

The Impact of Surgery on DCIS Outcomes: The Use of Mastectomy
Eun-Sil (Shelley) Hwang, M.D., M.P.H.
Assistant Professor of Surgery
University of California at San Francisco School of Medicine

8:50 a.m.  The Impact of Systemic Therapy on DCIS Outcomes
Sandra M. Swain, M.D.
Medical Director
Washington Cancer Institute
Washington Hospital Center
Professor of Medicine
Georgetown University
9:10 a.m. 

Communications Between Patients and Providers and Informed Decision-Making 

Joann G. Elmore M.D., M.P.H.
Professor of Medicine
Adjunct Professor of Epidemiology
University of Washington School of Medicine
Section Head, General Medicine
Harborview Medical Center

9:30 a.m.  Evidence-Based Practice Center Presentation IV: The Impact of Surgery, Radiation, and Systemic Treatment on Outcomes in Patients with Ductal Carcinoma in Situ
Robert L. Kane, M.D.
Director, Minnesota Evidence-based Practice Center
Professor
Minnesota Chair in Long-term Care and Aging
University of Minnesota School of Public Health
9:50 a.m.  Discussion
IV. What are the most critical research questions for the diagnosis and management of DCIS?
10:50 a.m. 

Molecular Markers for the Diagnosis and Management of DCIS
Kornelia Polyak, M.D., Ph.D.
Associate Professor of Medicine
Department of Medical Oncology
Dana-Farber Cancer Institute

11:10 a.m.  Imaging for the Diagnosis and Management of DCIS
Carl J. D'Orsi, M.D., F.A.C.R.
Professor of Radiology, Hematology, and Oncology
Director, Division of Breast Imaging
Emory University Hospital
11:30 a.m.  Quality of Life Issues and Outcomes Research in DCIS
Patricia A. Ganz, M.D.
Professor of Health Services and Medicine
School of Public Health and David Geffen School of Medicine
Director
Division of Cancer Prevention and Control Research
Jonsson Comprehensive Cancer Center
University of California, Los Angeles
11:50 a.m.  Discussion
12:20 p.m.  Adjournment


Thursday, September 24, 2009

9:00 a.m. Presentation of the Draft Consensus Statement
9:30 a.m. Public Discussion
11:00 a.m. Panel Meets in Executive Session
Adjournment
2:00 p.m. Press Telebriefing

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